Pulling Pinned Polymers and Unzipping DNA
نویسندگان
چکیده
منابع مشابه
Pulling pinned polymers and unzipping DNA.
We study a class of micromanipulation experiments, exemplified by the pulling apart of the two strands of double-stranded DNA. When the pulling force is increased to a critical value, an "unzipping" transition occurs. For random DNA sequences with short-ranged correlations, we obtain exact results for the number of monomers liberated and the specific heat, including the critical behavior at the...
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– We compare Monte Carlo simulations of knotted and unknotted polymers whose ends are connected to two parallel walls. The force f exerted on the polymer is measured as a function of the separation R between the walls. For unknotted polymers of several monomer numbers N , the product fN is a simple function of R/N , where ν 0.59. By contrast, knotted polymers exhibit strong finite-size effects ...
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We introduce a model of thermalized conformations in space of RNA -or single stranded DNAmolecules, which includes the possibility of hairpin formation. This model contains the usual secondary structure information, but extends it to the study of one element of the ternary structure, namely the end-to-end distance. The computed force-elongation characteristics is in good agreemement with some r...
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Experimental studies of the thermal denaturation of DNA yield a strong indication that the transition is first order. This transition has been theoretically studied since the early sixties, mostly within an approach in which the microscopic configurations of a DNA molecule are given by an alternating sequence of non-interacting bound segments and denaturated loops. Studies of these models negle...
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ژورنال
عنوان ژورنال: Physical Review Letters
سال: 2000
ISSN: 0031-9007,1079-7114
DOI: 10.1103/physrevlett.85.1572